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Issue 42, 2017
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MicroRNA detection at femtomolar concentrations with isothermal amplification and a biological nanopore

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Abstract

One of the greatest challenges faced by chemists and biologists is the detection of molecules at extremely low concentrations. This paper describes a method to detect ultra-low concentrations (1 femtomole) of nucleotides using isothermal amplification and a biological nanopore.

Graphical abstract: MicroRNA detection at femtomolar concentrations with isothermal amplification and a biological nanopore

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Publication details

The article was received on 13 Jun 2017, accepted on 25 Sep 2017 and first published on 27 Sep 2017


Article type: Communication
DOI: 10.1039/C7NR04215A
Citation: Nanoscale, 2017,9, 16124-16127
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    MicroRNA detection at femtomolar concentrations with isothermal amplification and a biological nanopore

    H. Zhang, M. Hiratani, K. Nagaoka and R. Kawano, Nanoscale, 2017, 9, 16124
    DOI: 10.1039/C7NR04215A

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