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Issue 32, 2017
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Atomic scale surface engineering of micro- to nano-sized pharmaceutical particles for drug delivery applications

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Abstract

Atomic layer deposition on pharmaceutical particles for drug delivery applications is demonstrated using assisted fluidized bed dry powder processing. Complete and conformal layering is achieved on particle sizes from the lower micron to upper nanometer range under near ambient conditions. As few as 2–14 atomic alumina layers alter particle properties: dissolution, dispersibility and heat transfer.

Graphical abstract: Atomic scale surface engineering of micro- to nano-sized pharmaceutical particles for drug delivery applications

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Publication details

The article was received on 08 May 2017, accepted on 25 Jun 2017 and first published on 27 Jun 2017


Article type: Communication
DOI: 10.1039/C7NR03261G
Citation: Nanoscale, 2017,9, 11410-11417
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    Atomic scale surface engineering of micro- to nano-sized pharmaceutical particles for drug delivery applications

    D. Zhang, M. J. Quayle, G. Petersson, J. R. van Ommen and S. Folestad, Nanoscale, 2017, 9, 11410
    DOI: 10.1039/C7NR03261G

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