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Real-Time Visualization and Sub-Diffraction Limit Localization of Nanometer-Scale Pore Formation by Dielectric Breakdown

Abstract

Herein, we introduce synchronous, real-time, electro-optical monitoring of nanopore formation by DB. Using the same principle as sub-diffraction microscopy, our nanopore localization platform based on wide-field microscopy and calcium indicators provides nanoscale sensitivity. This enables us to establish critical limitations of the fabrication process and improve its reliability. In particular, we find that under certain conditions multiple nanopores may form and that nanopores may preferentially localize at the membrane juncture, either of which potentially rendering nanopore sensing ineffective. As the breakdown parameters of silicon materials are highly manufacturer-specific, we anticipate that our visualization platform will enable users to easily optimize DB fabrication according to specific needs. Furthermore, our technique furthers the applicability of DB to more complicated architectures, such as membranes with selectively thinned regions and plasmonic nanowells.

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Supplementary files

Publication details

The article was received on 12 Apr 2017, accepted on 27 Sep 2017 and first published on 28 Sep 2017


Article type: Paper
DOI: 10.1039/C7NR02629C
Citation: Nanoscale, 2017, Accepted Manuscript
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    Real-Time Visualization and Sub-Diffraction Limit Localization of Nanometer-Scale Pore Formation by Dielectric Breakdown

    A. Zrehen, T. Gilboa and A. Meller, Nanoscale, 2017, Accepted Manuscript , DOI: 10.1039/C7NR02629C

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