Jump to main content
Jump to site search


Artificial Hagfish Protein Fibers with Ultra-High and Tunable Stiffness

Abstract

Stiff fibers are used as reinforcing phases in a wide range of high-performance composite materials. Silk is one of the most widely studied bio-fibers, but alternative materials with specific advantages are also being explored. Among these, native hagfish (Eptatretus stoutii) slime thread is an attractive protein-based polymer. These threads consist of coiled-coil intermediate filaments (IFs) as nano-scale building blocks, which can be transformed into extended β-sheet-containing chains upon draw-processing, resulting in fibers with impressive mechanical performance. Here, we report on artificial hagfish threads produced by recombinant protein expression, which were subsequently self-assembled into coiled-coil nanofilaments, concentrated, and processed into β-sheet-rich fibers by a “picking-up” method. These artificial fibers experienced mechanical performance enhancement during draw-processing. We exploited the Lysine content to covalently cross-link the draw-processed fibers and obtained moduli values (E) in tension as high as ~20 GPa, which is stiffer than most reported artificial proteinaceous materials.

Back to tab navigation

Supplementary files

Publication details

The article was received on 10 Apr 2017, accepted on 07 Aug 2017 and first published on 09 Aug 2017


Article type: Paper
DOI: 10.1039/C7NR02527K
Citation: Nanoscale, 2017, Accepted Manuscript
  •   Request permissions

    Artificial Hagfish Protein Fibers with Ultra-High and Tunable Stiffness

    J. Fu, P. Guerette, A. Pavesi, N. Horbelt, C. T. Lim, M. J. Harrington and A. Miserez, Nanoscale, 2017, Accepted Manuscript , DOI: 10.1039/C7NR02527K

Search articles by author

Spotlight

Advertisements