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Issue 19, 2017
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Recent progress in biomedical applications of persistent luminescence nanoparticles

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Abstract

Persistent luminescence nanoparticles (PLNPs) are an emerging group of promising luminescent materials that can remain luminescent after the excitation ceases. In the past decade, PLNPs with intriguing optical properties have been developed and their applications in biomedicine have been widely studied. Due to the ultra-long decay time of persistent luminescence, autofluorescence interference in biosensing and bioimaging can be efficiently eliminated. Moreover, PLNPs can remain luminescent for hours, making them valuable in bio-tracing. Also, persistent luminescence imaging can guide cancer therapy with a high signal-to-noise ratio (SNR) and superior sensitivity. Briefly, PLNPs are demonstrated to be a newly-emerging class of functional materials with unprecedented advantages in biomedicine. In this review, we summarized recent advances in the preparation of PLNPs and the applications of PLNPs in biosensing, bioimaging and cancer therapy.

Graphical abstract: Recent progress in biomedical applications of persistent luminescence nanoparticles

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Publication details

The article was received on 01 Mar 2017, accepted on 07 Apr 2017 and first published on 11 Apr 2017


Article type: Review Article
DOI: 10.1039/C7NR01488K
Citation: Nanoscale, 2017,9, 6204-6218
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    Recent progress in biomedical applications of persistent luminescence nanoparticles

    J. Wang, Q. Ma, Y. Wang, H. Shen and Q. Yuan, Nanoscale, 2017, 9, 6204
    DOI: 10.1039/C7NR01488K

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