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Issue 29, 2017
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Graphene oxide-stabilized perfluorocarbon emulsions for controlled oxygen delivery

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Abstract

Perfluorocarbon (PFC) emulsions are capable of absorbing large quantities of oxygen. They are widely used as blood alternates for quick oxygenation of tissues. However, they are unsuitable for applications where sustained oxygen supply is desired over an extended period of time. Here, we have designed a new PFC oxygen delivery system that combines perfluorodecalin with graphene oxide (GO), where GO acts both as an emulsifier and a stabilizing agent. The resulting emulsions (PFC@GO) release oxygen at least one order of magnitude slower than emulsions prepared with other common surfactants. The release rate can be controlled by varying the thickness of the GO layer. Controlled release of oxygen make these emulsions excellent oxygen carriers for applications where sustained oxygen delivery is required e.g. in tissue regeneration and vascular wound healing.

Graphical abstract: Graphene oxide-stabilized perfluorocarbon emulsions for controlled oxygen delivery

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Publication details

The article was received on 17 Jan 2017, accepted on 27 Jun 2017 and first published on 04 Jul 2017


Article type: Communication
DOI: 10.1039/C7NR00378A
Citation: Nanoscale, 2017,9, 10161-10166
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    Graphene oxide-stabilized perfluorocarbon emulsions for controlled oxygen delivery

    G. Jalani, D. Jeyachandran, R. Bertram Church and M. Cerruti, Nanoscale, 2017, 9, 10161
    DOI: 10.1039/C7NR00378A

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