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Transformation from Single-Mesoporous to Dual-Mesoporous Organosilica Nanoparticles


Transformation from single-mesoporous to dual-mesoporous structured organosilica nanoparticles can be achieved by simply varying the volume fraction of ethanol in the synthesis system, using lauryl sulfonate betaine and sodium dodecyl sulfonate as dual-templates. Core-shell structured dual-mesoporous organosilica nanoparticles possess smaller mesopores (4.0 nm) in the shell and flower-like larger mesopores (46 nm) in the core. Owing to the unique mesostructure, dual-mesoporous organosilica nanoparticles show high loading capacity and slow release rate for cargo molecules. The inside large mesopores can provide large storage space for the guest molecules and small mesopores in the outer shell act as nature valve, slowing the release. In addition, both single-mesoporous and dual-mesoporous organosilica nanoparticles exhibit low cell toxicity and excellent cell permeability.

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Publication details

The article was received on 16 Jan 2017, accepted on 06 Apr 2017 and first published on 07 Apr 2017

Article type: Paper
DOI: 10.1039/C7NR00363C
Citation: Nanoscale, 2017, Accepted Manuscript
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    Transformation from Single-Mesoporous to Dual-Mesoporous Organosilica Nanoparticles

    X. Wang, L. Zhou, Y. Liu, S. Yin, Z. Qiao and Q. Huo, Nanoscale, 2017, Accepted Manuscript , DOI: 10.1039/C7NR00363C

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