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Transformation from single-mesoporous to dual-mesoporous organosilica nanoparticles

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Abstract

Transformation from single-mesoporous to dual-mesoporous structured organosilica nanoparticles can be achieved by simply varying the volume fraction of ethanol in the synthesis system, using lauryl sulfonate betaine and sodium dodecyl sulfonate as dual-templates. Core–shell structured dual-mesoporous organosilica nanoparticles possess smaller mesopores (4.0 nm) in the shell and flower-like larger mesopores (46 nm) in the core. Owing to the unique mesostructure, dual-mesoporous organosilica nanoparticles show a high loading capacity and a slow release rate for cargo molecules. The large mesopores on the inside can provide a large storage space for the guest molecules and the small mesopores in the outer shell act as a natural valve, slowing the release. In addition, both single-mesoporous and dual-mesoporous organosilica nanoparticles, exhibit low cell toxicity and excellent cell permeability.

Graphical abstract: Transformation from single-mesoporous to dual-mesoporous organosilica nanoparticles

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Publication details

The article was received on 16 Jan 2017, accepted on 06 Apr 2017 and first published on 07 Apr 2017


Article type: Paper
DOI: 10.1039/C7NR00363C
Citation: Nanoscale, 2017, Advance Article
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    Transformation from single-mesoporous to dual-mesoporous organosilica nanoparticles

    X. Wang, L. Zhou, Y. Liu, S. Yin, Z. Qiao and Q. Huo, Nanoscale, 2017, Advance Article , DOI: 10.1039/C7NR00363C

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