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Enzyme-coated Janus nanoparticles that selectively bind cell receptors as a function of the concentration of glucose

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Abstract

A method is proposed for controlling the number of nanoparticles bound to cell membranes via RGDS peptide–integrin interactions. It consists of propelling nanoparticles bearing the peptides with enzymes (glucose oxidase), which disrupts biomolecular interactions as a function of the concentration of enzyme substrate (glucose).

Graphical abstract: Enzyme-coated Janus nanoparticles that selectively bind cell receptors as a function of the concentration of glucose

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Publication details

The article was received on 13 Jan 2017, accepted on 11 Apr 2017 and first published on 12 Apr 2017


Article type: Communication
DOI: 10.1039/C7NR00298J
Citation: Nanoscale, 2017, Advance Article
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    Enzyme-coated Janus nanoparticles that selectively bind cell receptors as a function of the concentration of glucose

    G. Rucinskaite, S. A. Thompson, S. Paterson and R. de la Rica, Nanoscale, 2017, Advance Article , DOI: 10.1039/C7NR00298J

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