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Issue 14, 2017
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A MnO2 nanosheet-assisted GSH detection platform using an iridium(III) complex as a switch-on luminescent probe

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Abstract

A rapid and sensitive detection platform for GSH has been constructed by combining a MnO2 nanosheet with a luminescent iridium(III) complex [Ir(Cl-phq)2(Cl-phen)]+. The MnO2 nanosheet was prepared by using a facile one-step approach and was characterized by TEM. The luminescence intensity of the detection platform responded linearly with the GSH concentration from 1 to 200 μM (R2 = 0.9951), and the detection limit for GSH was 0.13 μM. More importantly, practical application of the detection platform for visualizing the intracellular GSH distribution in living zebrafish has also been demonstrated.

Graphical abstract: A MnO2 nanosheet-assisted GSH detection platform using an iridium(iii) complex as a switch-on luminescent probe

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Publication details

The article was received on 25 Oct 2016, accepted on 12 Jan 2017 and first published on 13 Jan 2017


Article type: Paper
DOI: 10.1039/C6NR08357A
Citation: Nanoscale, 2017,9, 4677-4682
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    A MnO2 nanosheet-assisted GSH detection platform using an iridium(III) complex as a switch-on luminescent probe

    Z. Dong, L. Lu, C. Ko, C. Yang, S. Li, M. Lee, C. Leung and D. Ma, Nanoscale, 2017, 9, 4677
    DOI: 10.1039/C6NR08357A

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