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Issue 3, 2018
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Mitochondria-targeted ratiometric fluorescent detection of hydrazine with a fast response time

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Abstract

A ratiometric fluorescent probe 1 was synthesized, which exhibited high sensitivity and excellent selectivity for hydrazine recognition. Probe 1 can quantitatively detect hydrazine in the concentration range from 30 to 180 μM with a LOD of 2.1 μM. Furthermore, it displayed excellent selectivity, anti-interference over many nucleophilic species, biological species, metal ions and anions, and a fast response time (4 min). Due to its ability to target mitochondria, the response of hydrazine to this probe in a living cell was successfully tracked in a ratiometric manner via fluorescence imaging.

Graphical abstract: Mitochondria-targeted ratiometric fluorescent detection of hydrazine with a fast response time

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Publication details

The article was received on 31 Oct 2017, accepted on 21 Dec 2017 and first published on 21 Dec 2017


Article type: Paper
DOI: 10.1039/C7NJ04212D
Citation: New J. Chem., 2018,42, 2030-2035
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    Mitochondria-targeted ratiometric fluorescent detection of hydrazine with a fast response time

    Y. Ban, R. Wang, Y. Li, Z. An, M. Yu, C. Fang, L. Wei and Z. Li, New J. Chem., 2018, 42, 2030
    DOI: 10.1039/C7NJ04212D

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