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Contemporary progress in the synthesis and reactions of 2-aminobenzothiazole: a review

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Abstract

In the past few decades, heterocyclic compounds and their derivatives have gained popularity due to their prominent medicinal importance. The versatile and synthetically accessible 2-aminobenzothiazole scaffolds are quite fascinating for multiple applications in both synthetic organic chemistry and biological fields due to their potent pharmacological activities. A large number of efforts have been made to develop a wide range of methodologies for the synthesis of 2-aminobenzothiazole and its derivatives. Moreover, 2-aminobenzothiazole significantly serves as a reactant or a reaction intermediate for affording various fused heterocycles since NH2 and endocyclic N functions of 2-aminobenzothiazole are suitable to assist reactions with common bis electrophilic reagents to form a diverse fused heterocyclic scaffold. This review highlights various synthetic methodologies and chemical reactions of 2-aminobenzothiazole.

Graphical abstract: Contemporary progress in the synthesis and reactions of 2-aminobenzothiazole: a review

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Publication details

The article was received on 04 Oct 2017, accepted on 28 Nov 2017 and first published on 28 Nov 2017


Article type: Perspective
DOI: 10.1039/C7NJ03776G
Citation: New J. Chem., 2018, Advance Article
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    Contemporary progress in the synthesis and reactions of 2-aminobenzothiazole: a review

    T. L. Dadmal, S. D. Katre, M. C. Mandewale and R. M. Kumbhare, New J. Chem., 2018, Advance Article , DOI: 10.1039/C7NJ03776G

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