Jump to main content
Jump to site search

Issue 24, 2017
Previous Article Next Article

Dialkylgallium alkoxides – a tool for facile and stereoselective synthesis of PLA–drug conjugates

Author affiliations

Abstract

Herein, a method for the synthesis of PLA-(β-blocker) conjugates with a tunable stereostructure of the PLA fragment is demonstrated using stereoselective [R2Ga(μ-β-blocker)]2 catalysts and [R2Ga(μ-OR)]2/H-(β-blocker) catalytic systems for the ring-opening polymerisation (ROP) and immortal ring-opening polymerisation (iROP) of racemic lactide (rac-LA), respectively.

Graphical abstract: Dialkylgallium alkoxides – a tool for facile and stereoselective synthesis of PLA–drug conjugates

Back to tab navigation

Supplementary files

Publication details

The article was received on 18 Aug 2017, accepted on 09 Nov 2017 and first published on 10 Nov 2017


Article type: Letter
DOI: 10.1039/C7NJ03089D
Citation: New J. Chem., 2017,41, 14851-14854
  • Open access: Creative Commons BY license
  •   Request permissions

    Dialkylgallium alkoxides – a tool for facile and stereoselective synthesis of PLA–drug conjugates

    M. Cybularczyk-Cecotka, R. Zaremba, A. Hurko, A. Plichta, M. Dranka and P. Horeglad, New J. Chem., 2017, 41, 14851
    DOI: 10.1039/C7NJ03089D

    This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements