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Array-based detection of isomeric and analogous analytes employing synthetically modified fluorophore attached β-cyclodextrin derivatives

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Abstract

Reported herein is a sensitive and selective array-based sensing strategy based on differential interactions with three supramolecular cyclodextrin–fluorophore sensors. Each interaction results in a distinct fluorescence modulation response, and linear discriminant analyses of these responses results in 100% successful classification of three classes of isomeric analytes and two classes of analogous analytes. Calculated limits of detection for this system are at or near literature-reported levels of concern.

Graphical abstract: Array-based detection of isomeric and analogous analytes employing synthetically modified fluorophore attached β-cyclodextrin derivatives

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Publication details

The article was received on 10 Aug 2017, accepted on 23 Oct 2017 and first published on 23 Oct 2017


Article type: Paper
DOI: 10.1039/C7NJ02968C
Citation: New J. Chem., 2017, Advance Article
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    Array-based detection of isomeric and analogous analytes employing synthetically modified fluorophore attached β-cyclodextrin derivatives

    S. Chaudhuri, D. J. DiScenza, B. Smith, R. Yocum and M. Levine, New J. Chem., 2017, Advance Article , DOI: 10.1039/C7NJ02968C

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