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Development of a viscosity sensitive fluorescent probe for real-time monitoring of mitochondria viscosity

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Abstract

Using hemicyanine and carbazole as an acceptor and a donor, respectively, we designed and synthesized two new mitochondrial-targeted fluorescent viscosity probes (MHC-V1 and MHC-V2). The new probes were membrane-permeable and suitable for visualization of the changes of viscosity within the mitochondria of living cells.

Graphical abstract: Development of a viscosity sensitive fluorescent probe for real-time monitoring of mitochondria viscosity

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Publication details

The article was received on 25 Jun 2017, accepted on 03 Sep 2017 and first published on 04 Sep 2017


Article type: Letter
DOI: 10.1039/C7NJ02270K
Citation: New J. Chem., 2017, Advance Article
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    Development of a viscosity sensitive fluorescent probe for real-time monitoring of mitochondria viscosity

    K. Zhou, M. Ren, B. Deng and W. Lin, New J. Chem., 2017, Advance Article , DOI: 10.1039/C7NJ02270K

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