Issue 20, 2017
From the journal:

New Journal of Chemistry

Development of a viscosity sensitive fluorescent probe for real-time monitoring of mitochondria viscosity†

Kai Zhou, ORCID logo a   Mingguang Ren, ORCID logo a   Beibei Deng ORCID logo a  and  Weiying Lin ORCID logo *a  

* Corresponding authors

a Institute of Fluorescent Probes for Biological Imaging, School of Chemistry and Chemical Engineering, School of Materials Science and Engineering, University of Jinan, Jinan, Shandong, P. R. China
E-mail: weiyinglin2013@163.com

Abstract

Using hemicyanine and carbazole as an acceptor and a donor, respectively, we designed and synthesized two new mitochondrial-targeted fluorescent viscosity probes (MHC-V1 and MHC-V2). The new probes were membrane-permeable and suitable for visualization of the changes of viscosity within the mitochondria of living cells.

Graphical abstract: Development of a viscosity sensitive fluorescent probe for real-time monitoring of mitochondria viscosity

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Article information

DOI
https://doi.org/10.1039/C7NJ02270K
Article type
Letter
Submitted
25 Jun 2017
Accepted
03 Sep 2017
First published
04 Sep 2017

New J. Chem., 2017,41, 11507-11511

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Development of a viscosity sensitive fluorescent probe for real-time monitoring of mitochondria viscosity

K. Zhou, M. Ren, B. Deng and W. Lin, New J. Chem., 2017, 41, 11507 DOI: 10.1039/C7NJ02270K

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