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Revealing the biodistribution and clearance of Ag2Se near-infrared quantum dots in mice

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Abstract

The biodistribution and clearance in mice of near-infrared (NIR) ultra-small Ag2Se quantum dots (QDs) were systematically studied. The ICP-MS quantitative assessment and biodistribution fluorescent images of Ag2Se QDs in mouse organs demonstrated that the Ag2Se QDs could be cleared quickly from the mice body mostly by renal excretion without significant long-term organs accumulation. Pathological analysis, blood biochemical analysis, and body weight results also showed that the Ag2Se QDs do not cause appreciable toxicity in vivo.

Graphical abstract: Revealing the biodistribution and clearance of Ag2Se near-infrared quantum dots in mice

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Publication details

The article was received on 13 Jun 2017, accepted on 12 Sep 2017 and first published on 18 Sep 2017


Article type: Paper
DOI: 10.1039/C7NJ02126G
Citation: New J. Chem., 2017, Advance Article
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    Revealing the biodistribution and clearance of Ag2Se near-infrared quantum dots in mice

    X. Ge, Z. Zhang, Z. Xie, R. Cui and D. Pang, New J. Chem., 2017, Advance Article , DOI: 10.1039/C7NJ02126G

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