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Issue 20, 2017
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A highly sensitive and selective fluorescent probe for N2H4 in air and living cells

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Abstract

Hydrazine (N2H4) is considered as an environmental contaminant and a potential carcinogen, and its large-scale application could pose a great threat to the environment and human health. In the present work, a new colorimetric and fluorescent probe NAA was developed for the sensitive and selective detection of N2H4 in air and aqueous solution. The probe shows a selective response to N2H4 against various interferences (e.g., anions, cations, amines and small biomolecules) and a detection limit as low as 0.716 ppb (22.5 nM) far below the threshold limit value (10 ppb) of EPA. By observing the color and fluorescence changes, the test strip coated with NAA provides an economical and convenient tool for the rapid detection of N2H4 gas. Moreover, the probe was proved to possess low cytotoxicity as well as good membrane permeability and thus shows great potential in N2H4 imaging in living cells.

Graphical abstract: A highly sensitive and selective fluorescent probe for N2H4 in air and living cells

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Publication details

The article was received on 02 Jun 2017, accepted on 28 Jul 2017 and first published on 31 Jul 2017


Article type: Paper
DOI: 10.1039/C7NJ01943B
Citation: New J. Chem., 2017,41, 11891-11897
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    A highly sensitive and selective fluorescent probe for N2H4 in air and living cells

    J. Cui, G. Gao, H. Zhao, Y. Liu, H. Nie and X. Zhang, New J. Chem., 2017, 41, 11891
    DOI: 10.1039/C7NJ01943B

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