Issue 18, 2017

Photophysical properties of quinoxalin-2(1H)-ones: application in the preparation of an azide-based fluorogenic probe for the detection of hydrogen sulfide

Abstract

Quinoxalinones are widely exploited for their biological activities, but more rarely for their fluorescence behavior, partly due to a lack of data. Herein, we investigated the photophysical properties of selected 3-benzoylquinoxalin-2-ones and their NaBH4-reduced products, obtained by the rearrangement of benzodiazepin-2-ones. To illustrate their potential, a quinoxalinone-based chemoprobe for the specific detection of hydrogen sulfide was investigated.

Graphical abstract: Photophysical properties of quinoxalin-2(1H)-ones: application in the preparation of an azide-based fluorogenic probe for the detection of hydrogen sulfide

Supplementary files

Article information

Article type
Paper
Submitted
29 May 2017
Accepted
28 Jul 2017
First published
31 Jul 2017

New J. Chem., 2017,41, 10432-10437

Photophysical properties of quinoxalin-2(1H)-ones: application in the preparation of an azide-based fluorogenic probe for the detection of hydrogen sulfide

K. Renault, P. Renard and C. Sabot, New J. Chem., 2017, 41, 10432 DOI: 10.1039/C7NJ01893B

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