Issue 18, 2017
From the journal:

New Journal of Chemistry

Synthesis of novel fused chromone–pyrimidine hybrids and 2,4,5-trisubstituted pyrimidine derivatives via ANRORC rearrangement†

M. Sambaiah,ab   K. Raghavulu,a   K. Shiva Kumar,b   Satyanarayana Yennama  and  Manoranjan Behera ORCID logo *a  

* Corresponding authors

a Chemistry Services, GVK Biosciences Pvt. Ltd, Survey No's: 125 (part) & 126, IDA Mallapur, Hyderabad-500076, Telangana State, India
E-mail: Manoranjan.Behera@gvkbio.com

b Department of Chemistry, GITAM University, Hyderabad Campus, Rudraram Village, Patancheru Mandal, Sangareddy Dist., Telangana State, India

Abstract

A facile and versatile procedure for the synthesis of functionalized novel 2,5-diphenyl-5H-chromeno[4,3-d]pyrimidin-5-ol and (2,4-diphenylpyrimidin-5-yl) (2-hydroxyphenyl) methanone has been described. The key step in the synthesis involves the ANRORC reaction of 3-benzoyl chromones with benzamidines.

Graphical abstract: Synthesis of novel fused chromone–pyrimidine hybrids and 2,4,5-trisubstituted pyrimidine derivatives via ANRORC rearrangement

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Article information

DOI
https://doi.org/10.1039/C7NJ01839H
Article type
Paper
Submitted
25 May 2017
Accepted
03 Aug 2017
First published
03 Aug 2017

New J. Chem., 2017,41, 10020-10026

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Synthesis of novel fused chromone–pyrimidine hybrids and 2,4,5-trisubstituted pyrimidine derivatives via ANRORC rearrangement

M. Sambaiah, K. Raghavulu, K. Shiva Kumar, S. Yennam and M. Behera, New J. Chem., 2017, 41, 10020 DOI: 10.1039/C7NJ01839H

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