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High Efficient Approach for Hypochlorous Acid Sensing in Water Samples and Living Cells Based on Acylhydrazone Schiff Base Functionalized Fluorescent Probes

Abstract

designed and presented for sensing HClO in biological and environmental water samples with prominent sensitivity, photostability and selectivity over other ROS/RNS, ions and biomolecules through the irreversible HClO−promoted oxidation and hydrolyzation reaction in formation of the ring−opened product fluorescein. Successfully, detecting of HClO in practical swimming pool water and tap water samples as well as cell imaging in living L929 and MG–63 cells recommended the probes could not only help verifying the HClO concentration in practical water samples, but also serve as promising tools to exploit and elucidate functions of HClO in biological cells, organisms and processes.

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Publication details

The article was received on 26 Apr 2017, accepted on 11 Sep 2017 and first published on 12 Sep 2017


Article type: Paper
DOI: 10.1039/C7NJ01383C
Citation: New J. Chem., 2017, Accepted Manuscript
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    High Efficient Approach for Hypochlorous Acid Sensing in Water Samples and Living Cells Based on Acylhydrazone Schiff Base Functionalized Fluorescent Probes

    Z. Yang, Y. He, X. Liu, S. Zhao, Z. Yang and S. Yang, New J. Chem., 2017, Accepted Manuscript , DOI: 10.1039/C7NJ01383C

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