Jump to main content
Jump to site search


Deep eutectic liquid organic salt as a new solvent for carrier-mediated hollow fiber liquid phase microextraction of lead from whole blood followed by electrothermal atomic absorption spectrometry

Abstract

In the present work, for the first time, a new carrier-mediated hollow fiber liquid phase microextraction (CM-HFLPME) was applied for the determination of lead in whole blood samples by means of ETAAS. Lead was extracted from 17 mL of an acidic sample solution into 1-octanol containing N,N,N-cetyltrimethyl ammonium bromid (CTAB) and finally back-extracted into 25 µL of deep eutectic solvent (DES) containing KClO4 as the receiving phase. The effects of different variables on the extraction efficiency were considered using a central composite design. Under the optimized conditions, a preconcentration factor of 33 was obtained. LOD and LOQ were found to be 0.1 and 0.4 ng mL-1, respectively. The calibration curve was linear within the range of 1–200 ng mL-1 (r2 > 0.9915). RSD% values (n = 3) of 4.4% and 2.3% were obtained at the concentrations of 5.0 and 20 ng mL-1, respectively. Finally, the obtained results for lead contents in two control and test whole blood samples were compared with lead content of opium samples to investigate the correlation between them.

Back to tab navigation

Supplementary files

Publication details

The article was received on 20 Mar 2017, accepted on 12 Jun 2017 and first published on 14 Jun 2017


Article type: Paper
DOI: 10.1039/C7NJ00922D
Citation: New J. Chem., 2017, Accepted Manuscript
  •   Request permissions

    Deep eutectic liquid organic salt as a new solvent for carrier-mediated hollow fiber liquid phase microextraction of lead from whole blood followed by electrothermal atomic absorption spectrometry

    L. Alavi, S. Seidi, A. Jabbri and T. Baheri, New J. Chem., 2017, Accepted Manuscript , DOI: 10.1039/C7NJ00922D

Search articles by author

Spotlight

Advertisements