Jump to main content
Jump to site search


PEGylated molybdenum dichalcogenide (PEG-MoS2) nanosheets with enhanced peroxidase-like activity for the colorimetric detection of H2O2

Author affiliations

Abstract

To improve the peroxidase-like activity of molybdenum dichalcogenides (MoS2), surface modification, such as combing with monometallic or bimetallic nanoparticles, is of great and widespread interest. However, only a few studies have been reported on the modification of MoS2 with non-metallic materials. Herein, we report a study on the peroxidase-like activity of novel PEGylated MoS2 (PEG-MoS2) nanosheets prepared using a simple liquid-phase exfoliation and pegylation process. Compared to the undecorated MoS2 nanosheets, PEG-MoS2 nanosheets have improved water dispersiblity and stability, which are beneficial for improving the peroxidase-like activity, as well as the catalysis velocity and affinity for TMB or H2O2. Based on PEGylated MoS2, we successfully established a new platform for the colorimetric detection of H2O2 with a limit of detection (LOD) of 1.18 μM, which is comparable to that of the majority of the reported enzyme mimics of inorganic graphene analogues. More importantly, the as-prepared PEG-MoS2 nanosheets are environmentally friendly, water dispersible, low cytotoxic, and easily prepared, which indicate that PEG-MoS2 is a type of promising enzyme mimics and extremely likely to be applied in cell-based assay systems without any adverse reactions.

Graphical abstract: PEGylated molybdenum dichalcogenide (PEG-MoS2) nanosheets with enhanced peroxidase-like activity for the colorimetric detection of H2O2

Back to tab navigation

Supplementary files

Publication details

The article was received on 18 Mar 2017, accepted on 04 Jun 2017 and first published on 05 Jun 2017


Article type: Paper
DOI: 10.1039/C7NJ00899F
Citation: New J. Chem., 2017, Advance Article
  •   Request permissions

    PEGylated molybdenum dichalcogenide (PEG-MoS2) nanosheets with enhanced peroxidase-like activity for the colorimetric detection of H2O2

    H. Zhao, Y. Li, B. Tan, Y. Zhang, X. Chen and X. Quan, New J. Chem., 2017, Advance Article , DOI: 10.1039/C7NJ00899F

Search articles by author

Spotlight

Advertisements