Jump to main content
Jump to site search


Pd(NHC)PEPPSI-diazonium salts: an efficient blend for the decarboxylative Sonogashira cross coupling reaction

Author affiliations

Abstract

An efficient N-heterocyclic carbene based Pd complex is described for the de-carboxylative Sonogashira coupling reaction with diazonium salts under ligand and co-catalyst free conditions. Pd(NHC)PEPPSI not only offers an air and moisture stable pre-catalyst but also efficiently catalyzes the reaction with lower loading. Various aryl and hetero aryl diazonium salts undergo an sp–sp2 cross coupling reaction with alkynyl acid to give good to excellent yields of substituted acetylene derivatives. The diazonium salts serve as efficient, easily available, and inexpensive aryl surrogates over conventional aryl halides, triflates, oxalate, and sulphamate.

Graphical abstract: Pd(NHC)PEPPSI-diazonium salts: an efficient blend for the decarboxylative Sonogashira cross coupling reaction

Back to tab navigation

Supplementary files

Publication details

The article was received on 16 Mar 2017, accepted on 09 Jun 2017 and first published on 09 Jun 2017


Article type: Paper
DOI: 10.1039/C7NJ00877E
Citation: New J. Chem., 2017, Advance Article
  •   Request permissions

    Pd(NHC)PEPPSI-diazonium salts: an efficient blend for the decarboxylative Sonogashira cross coupling reaction

    J. M. Bhojane, V. G. Jadhav and J. M. Nagarkar, New J. Chem., 2017, Advance Article , DOI: 10.1039/C7NJ00877E

Search articles by author

Spotlight

Advertisements