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Convenient KI-catalyzed regioselective synthesis of 2-sulfonylindoles using water as solvent

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Abstract

A convenient procedure is developed for the preparation of 2-sulfonylindoles from indoles and sodium sulfinates catalyzed by KI in water. This environmentally benign 2-sulfonylation of indoles proceeds efficiently under mild conditions, affording the products with high regioselectivity and in moderate to good yields.

Graphical abstract: Convenient KI-catalyzed regioselective synthesis of 2-sulfonylindoles using water as solvent

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Publication details

The article was received on 09 Feb 2017, accepted on 24 Apr 2017 and first published on 26 Apr 2017


Article type: Letter
DOI: 10.1039/C7NJ00474E
Citation: New J. Chem., 2017, Advance Article
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    Convenient KI-catalyzed regioselective synthesis of 2-sulfonylindoles using water as solvent

    H. Li, X. Wang and J. Yan, New J. Chem., 2017, Advance Article , DOI: 10.1039/C7NJ00474E

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