Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.



Cyclometalated ruthenium complexes from naturally occurring quinones: studies on their photophysical features, computational details and trypanocidal activity

Author affiliations

Abstract

Phenazinic ligands and Ru(II)-based complexes were synthesized from natural products lapachol and lawsone and evaluated against T. cruzi, the etiological agent of Chagas disease. These new ruthenium compounds could provide promising trypanocidal drugs. Besides synthesis and trypanocidal activity, this paper reports photophysical features and computational details of the compounds. The fluorescent trypanocidal substances are promising derivatives for further studies aiming to find molecules active against parasites associated with neglected diseases.

Graphical abstract: Cyclometalated ruthenium complexes from naturally occurring quinones: studies on their photophysical features, computational details and trypanocidal activity

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 01 Feb 2017, accepted on 16 Mar 2017 and first published on 17 Mar 2017


Article type: Paper
DOI: 10.1039/C7NJ00379J
Citation: New J. Chem., 2017, Advance Article
  •   Request permissions

    Cyclometalated ruthenium complexes from naturally occurring quinones: studies on their photophysical features, computational details and trypanocidal activity

    C. M. de Souza, R. C. Silva, P. O. Fernandes, J. D. de Souza Filho, H. A. Duarte, M. H. Araujo, C. A. de Simone, S. L. de Castro, R. F. S. Menna-Barreto, C. P. Demicheli and E. N. da Silva Júnior, New J. Chem., 2017, Advance Article , DOI: 10.1039/C7NJ00379J

Search articles by author