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Cysteine, Homocysteine and Glutathione guided hierarchical self-assemblies of spherical silver nanoparticles paving the way for their naked eye discrimination in human serum

Abstract

Herein, we are unraveling the naked eye discrimination of three important biothiols viz., Cysteine, Homocysteine and Glutathione through silver nanoparticles immobilized over an azonaphthol. This visual detection is an outcome of three hierarchical self-assemblies in the form of flowers, thorns and petals guided by Cysteine, Homocysteine and Glutathione respectively. The bright yellow silver nanoprobe displayed bluish gray colour with Cysteine, purple pink with Homocysteine and orange colour with Glutathione with their Lowest detection limits of 260nM, 10 nM and 4.11 µM respectively. The same nanoprobe was successful in detecting the above mentioned biothiols in the human serum also.

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Publication details

The article was received on 02 Jan 2017, accepted on 13 Apr 2017 and first published on 17 Apr 2017


Article type: Paper
DOI: 10.1039/C7NJ00011A
Citation: New J. Chem., 2017, Accepted Manuscript
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    Cysteine, Homocysteine and Glutathione guided hierarchical self-assemblies of spherical silver nanoparticles paving the way for their naked eye discrimination in human serum

    I. Sanskriti and K. K. Upadhyay, New J. Chem., 2017, Accepted Manuscript , DOI: 10.1039/C7NJ00011A

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