Jump to main content
Jump to site search


Highly efficient green synthesis of α-hydroxyphosphonates using a recyclable choline hydroxide catalyst

Author affiliations

Abstract

Choline hydroxide has been found to be an efficient basic ionic liquid catalyst for the synthesis of α-hydroxyphosphonates. Hydrophosphonylation of aldehydes was performed via the nucleophilic addition of diethylphosphite to aldehydic carbonyl compounds, in the presence of choline hydroxide under neat as well as solvent conditions. A wide array of substrates, including aromatic, fused aromatic, and heterocyclic aldehydes, were efficiently converted to their corresponding products in good yields. This protocol provides an alternative method for the straightforward synthesis of α-hydroxyphosphonates in high yields.

Graphical abstract: Highly efficient green synthesis of α-hydroxyphosphonates using a recyclable choline hydroxide catalyst

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 16 Dec 2016, accepted on 12 May 2017 and first published on 15 May 2017


Article type: Paper
DOI: 10.1039/C6NJ03948K
Citation: New J. Chem., 2017, Advance Article
  •   Request permissions

    Highly efficient green synthesis of α-hydroxyphosphonates using a recyclable choline hydroxide catalyst

    R. M. N. Kalla, Y. Zhang and I. Kim, New J. Chem., 2017, Advance Article , DOI: 10.1039/C6NJ03948K

Search articles by author