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Antipseudomonal activity enhancement of luminescent iridium(III) dipyridylamine complexes under visible blue light

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Abstract

Cyclometallated iridium(III) dipyridylamine complexes present antibacterial activity against P. aeruginosa, a highly resistant pathogenic bacterium. This activity is increased when the complex is conjugated to biotin, a bacterial nutrient, and a MIC of 4 μM (4 μg mL−1) has been observed. The irradiation of P. aeruginosa cultures with blue LED light potentiates the anti-bacterial activities of these iridium(III) complexes when they are conjugated to a glycoside.

Graphical abstract: Antipseudomonal activity enhancement of luminescent iridium(iii) dipyridylamine complexes under visible blue light

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Publication details

The article was received on 12 Sep 2017, accepted on 08 Nov 2017 and first published on 08 Nov 2017


Article type: Paper
DOI: 10.1039/C7MT00262A
Citation: Metallomics, 2017, Advance Article
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    Antipseudomonal activity enhancement of luminescent iridium(III) dipyridylamine complexes under visible blue light

    E. Sauvageot, M. Elie, S. Gaillard, R. Daniellou, P. Fechter, I. J. Schalk, V. Gasser, J.-L. Renaud and G. L. A. Mislin, Metallomics, 2017, Advance Article , DOI: 10.1039/C7MT00262A

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