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High performance photosensitizers with aggregation-induced emission for image-guided photodynamic anticancer therapy

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Abstract

A series of D–A′–π–A type photosensitizers, AP3 and AP4, were designed and synthesized to show strong aggregation-induced far red and near infrared emission and very effective 1O2 generation simultaneously. In comparison with the most widely used photosensitizer, Ce6 nanoparticles, AP4 nanoparticles showed over 10-fold higher fluorescence quantum yield, and more than 3-fold higher 1O2 generation efficiency, and have been successfully used for image-guided photodynamic anticancer therapy.

Graphical abstract: High performance photosensitizers with aggregation-induced emission for image-guided photodynamic anticancer therapy

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Publication details

The article was received on 25 Jun 2017, accepted on 18 Aug 2017 and first published on 18 Aug 2017


Article type: Communication
DOI: 10.1039/C7MH00469A
Citation: Mater. Horiz., 2017, Advance Article
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    High performance photosensitizers with aggregation-induced emission for image-guided photodynamic anticancer therapy

    W. Wu, D. Mao, S. Xu, S. Ji, F. Hu, D. Ding, D. Kong and B. Liu, Mater. Horiz., 2017, Advance Article , DOI: 10.1039/C7MH00469A

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