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MedChemComm

Research and review articles in medicinal chemistry and related drug discovery science; the official journal of the European Federation for Medicinal Chemistry

Research Article

Discovery of a potent protein kinase D inhibitor: insights in the binding mode of pyrazolo[3,4-d]pyrimidine analogues

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Corresponding authors
a
Department of Chemistry, Molecular Design and Synthesis, KU Leuven, Celestijnenlaan 200F, 3001 Leuven, Belgium
E-mail: wim.deborggraeve@kuleuven.be
b
Department of Cellular and Molecular Medicine, Laboratory of Protein Phosphorylation and Proteomics, KU Leuven, Herestraat 49 box 901, 3000 Leuven, Belgium
c
Department of Chemistry, Laboratory of Biomolecular Modeling and Design, KU Leuven, Celestijnenlaan 200G, 3001 Leuven, Belgium
Med. Chem. Commun., 2017,8, 640-646

DOI: 10.1039/C6MD00675B
Received 02 Dec 2016, Accepted 31 Jan 2017
First published online 09 Feb 2017
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Supplementary Info