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Research and review articles in medicinal chemistry and related drug discovery science; the official journal of the European Federation for Medicinal Chemistry

Research Article

Identification of 4-N-[2-(4-phenoxyphenyl)ethyl]quinazoline-4,6-diamine as a novel, highly potent and specific inhibitor of mitochondrial complex I

Corresponding authors
Johann Wolfgang Goethe-University Frankfurt, Max-von-Laue-Straße 7, D-60438 Frankfurt am Main, Germany
E-mail: Nasiri@nmr.uni-frankfurt.de
Department of Anaesthesiology, Intensive-Care Medicine and Pain Therapy, University Hospital Frankfurt, 60590 Frankfurt am Main, Germany
Structural Bioenergetics Group, Institute of Biochemistry II, Medical School, Goethe-University, 60438 Frankfurt am Main, Germany
Cluster of Excellence Frankfurt “Macromolecular Complexes,”, Goethe-University, 60438 Frankfurt am Main, Germany
Med. Chem. Commun., 2017,8, 657-661

DOI: 10.1039/C6MD00655H
Received 26 Nov 2016, Accepted 17 Feb 2017
First published online 20 Feb 2017
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Supplementary Info