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A new droplet-forming fluidic junction for the generation of highly compartmentalised capsules

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Abstract

A new oscillatory microfluidic junction is described, which enables the consistent formation of highly uniform and complex double emulsions, and is demonstrated for the encapsulation of four different reagents within the inner droplets (called cores) of the double emulsion droplets. Once the double emulsion droplets had attained a spherical form, the cores assumed specific 3D arrangements, the orchestration of which appeared to depend upon the specific emulsion morphology. Such double emulsion droplets were used as templates to produce highly compartmentalised microcapsules and multisomes. Based on these construct models, we numerically demonstrated a model chemical reaction sequence between and within the liquid cores. This work could provide a platform to perform space/time-dependent applications, such as programmed experiments, synthesis, and delivery systems.

Graphical abstract: A new droplet-forming fluidic junction for the generation of highly compartmentalised capsules

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Publication details

The article was received on 13 Jun 2017, accepted on 14 Jul 2017 and first published on 14 Jul 2017


Article type: Paper
DOI: 10.1039/C7LC00618G
Citation: Lab Chip, 2017, Advance Article
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    A new droplet-forming fluidic junction for the generation of highly compartmentalised capsules

    J. Li and D. A. Barrow, Lab Chip, 2017, Advance Article , DOI: 10.1039/C7LC00618G

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