Jump to main content
Jump to site search

Issue 24, 2017
Previous Article Next Article

Transition-metal-free and organic solvent-free conversion of N-substituted 2-aminobiaryls into corresponding carbazoles via intramolecular oxidative radical cyclization induced by peroxodisulfate

Author affiliations

Abstract

An atom-economical and environmentally benign approach for the synthesis of N-substituted carbazoles from analogous 2-aminobiaryls using peroxodisulfate in water is reported. The reactions proceeded through an intramolecular oxidative radical cyclization of N-substituted 2-aminobiaryls with in situ reoxidation of the resulting radical species. When compared to known methods for the synthesis of N-substituted carbazoles from 2-amidobiaryls, this protocol is practical, efficient and does not require a transition metal catalyst or toxic organic solvents.

Graphical abstract: Transition-metal-free and organic solvent-free conversion of N-substituted 2-aminobiaryls into corresponding carbazoles via intramolecular oxidative radical cyclization induced by peroxodisulfate

Back to tab navigation

Supplementary files

Publication details

The article was received on 18 Oct 2017, accepted on 13 Nov 2017 and first published on 13 Nov 2017


Article type: Paper
DOI: 10.1039/C7GC03130K
Citation: Green Chem., 2017,19, 5854-5861
  •   Request permissions

    Transition-metal-free and organic solvent-free conversion of N-substituted 2-aminobiaryls into corresponding carbazoles via intramolecular oxidative radical cyclization induced by peroxodisulfate

    P. Natarajan, Priya and D. Chuskit, Green Chem., 2017, 19, 5854
    DOI: 10.1039/C7GC03130K

Search articles by author

Spotlight

Advertisements