Jump to main content
Jump to site search


Water excellent solvent for the synthesis of bifunctionalized cyclopentenones from furfural

Abstract

Chiral cyclopentenones are important precursors in the asymmetric synthesis of target molecules. In particular, C-2 amino cyclopentenones could be utilised as intermediates towards antitumor natural products. On the basis of our previous experiences, we report an environmental friendly protocol for the synthesis in water of bifunctionalised cyclopentenones from furfural. The use of water and MW gives high regioselectivity and good to excellent yields. The reaction can be realized in short time with various nucleophiles.

Back to tab navigation

Supplementary files

Publication details

The article was received on 29 Jul 2017, accepted on 15 Sep 2017 and first published on 15 Sep 2017


Article type: Paper
DOI: 10.1039/C7GC02303K
Citation: Green Chem., 2017, Accepted Manuscript
  •   Request permissions

    Water excellent solvent for the synthesis of bifunctionalized cyclopentenones from furfural

    M. Nardi, P. Costanzo, A. De Nino, M. L. Di Gioia, F. Olivito, G. Sindona and A. Procopio, Green Chem., 2017, Accepted Manuscript , DOI: 10.1039/C7GC02303K

Search articles by author

Spotlight

Advertisements