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Issue 21, 2017
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Design and evolution of the BMS process greenness scorecard

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Abstract

An accurate and comprehensive assessment of the environmental, health and safety impacts of a chemical process is critical to the design and implementation of greener, more benign and inherently safer processes. Over the past 15 years at BMS, we have developed a Process Greenness Scorecard to capture and analyse a number of metrics and attributes for each step in the synthetic sequence used to produce an API. This manuscript describes the design and evolution of the scoring methodology and implementation of the resulting scorecard, from an initial Excel-based tool to the current web-based format.

Graphical abstract: Design and evolution of the BMS process greenness scorecard

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Publication details

The article was received on 20 Jul 2017, accepted on 03 Oct 2017 and first published on 03 Oct 2017


Article type: Paper
DOI: 10.1039/C7GC02190A
Citation: Green Chem., 2017,19, 5163-5171
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    Design and evolution of the BMS process greenness scorecard

    D. K. Leahy, E. M. Simmons, V. Hung, J. T. Sweeney, W. F. Fleming and M. Miller, Green Chem., 2017, 19, 5163
    DOI: 10.1039/C7GC02190A

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