Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance upgrade on Thursday 4th of May 2017 from 8.00am to 9.00am (BST).

During this time our websites will be offline temporarily. If you have any questions please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.



An efficient and eco-friendly synthesis of 2-pyridones and functionalized azaxanthone frameworks via indium triflate catalyzed domino reaction

Author affiliations

Abstract

A green and efficient one-pot method has been developed for the synthesis of 2-pyridone and functionalized azaxanthone frameworks using indium triflate as an environmentally friendly, reusable catalyst. In this one-pot reaction, 3-formylchromones display a diverse pattern of reactivity upon reaction with different classes of alkenes. An indium triflate-promoted reaction with (Z)-N-methyl-1-(methylthio)-2-nitroethenamine leads to 3-formylchromone annulations to 2-pyridone and analogues via a remarkably facile chromone ring opening. The analogous reaction with N,N’-dimethyl-2-nitro-ethene-1,1-diamine results in the formation of synthetically useful functionalized azaxanthones via a 6π-electrocyclization reaction.

Graphical abstract: An efficient and eco-friendly synthesis of 2-pyridones and functionalized azaxanthone frameworks via indium triflate catalyzed domino reaction

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 13 Dec 2016, accepted on 30 Mar 2017 and first published on 03 Apr 2017


Article type: Communication
DOI: 10.1039/C6GC03440C
Citation: Green Chem., 2017, Advance Article
  •   Request permissions

    An efficient and eco-friendly synthesis of 2-pyridones and functionalized azaxanthone frameworks via indium triflate catalyzed domino reaction

    N. Poomathi, P. T. Perumal and S. Ramakrishna, Green Chem., 2017, Advance Article , DOI: 10.1039/C6GC03440C

Search articles by author