Jump to main content
Jump to site search

Issue 6, 2017
Previous Article Next Article

Toolbox study for application of hydrogen peroxide as a versatile, safe and industrially-relevant green oxidant in continuous flow mode

Author affiliations

Abstract

Hydrogen peroxide embodies an ideal oxidant in terms of atom-economy, availability and green metrics. However, its use has been limited because of risks associated with disproportionation and the exothermic potential of oxidizing reaction mixtures. This study aims to showcase the versatility of hydrogen peroxide in a range of oxidations, while ensuring that such processes operate practically and with a defined and minimized risk. To offset the hazards of using peroxides, continuous-flow equipment was utilized to limit the volume of unquenched peroxides and to maintain process control. A methodological approach was established relying on kinetic and calorimetric understanding. Finally, scalability was highlighted in an organocatalysed heterocyclic N-oxidation using a cascade of stirred tank reactors with nitrogen flushing.

Graphical abstract: Toolbox study for application of hydrogen peroxide as a versatile, safe and industrially-relevant green oxidant in continuous flow mode

Back to tab navigation

Supplementary files

Publication details

The article was received on 19 Oct 2016, accepted on 18 Nov 2016 and first published on 23 Nov 2016


Article type: Paper
DOI: 10.1039/C6GC02899C
Citation: Green Chem., 2017,19, 1439-1448
  •   Request permissions

    Toolbox study for application of hydrogen peroxide as a versatile, safe and industrially-relevant green oxidant in continuous flow mode

    B. Martin, J. Sedelmeier, A. Bouisseau, P. Fernandez-Rodriguez, J. Haber, F. Kleinbeck, S. Kamptmann, F. Susanne, P. Hoehn, M. Lanz, L. Pellegatti, F. Venturoni, J. Robertson, M. C. Willis and B. Schenkel, Green Chem., 2017, 19, 1439
    DOI: 10.1039/C6GC02899C

Search articles by author

Spotlight

Advertisements