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Molecular Targets and Mechanisms of Bioactive Peptides Against Metabolic Syndromes

Abstract

Bioactive peptides present ubiquitously in all living organisms and play critical roles ranging from protection against infection as the key element of innate immunity, regulating blood pressure and glucose levels, to reducing the sign of ageing by killing senescent cells. Bioactive peptides are also encrypted within food protein sequences that can be released during proteolysis or food processing. These specific food protein fragments are reported to have vast potential for improving human health and preventing metabolic diseases through their impact on inflammation, blood pressure, obesity and type-2 diabetes. This review mainly focus on the molecular targets and the underlying mechanisms of bioactive peptides against various metabolic syndromes including inflammation, high blood pressure, obesity, and type-2 diabetes, to provide new insights and perspectives on the potential of bioactive peptides for the management of metabolic syndromes.

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Publication details

The article was received on 26 Aug 2017, accepted on 08 Nov 2017 and first published on 09 Nov 2017


Article type: Review Article
DOI: 10.1039/C7FO01323J
Citation: Food Funct., 2017, Accepted Manuscript
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    Molecular Targets and Mechanisms of Bioactive Peptides Against Metabolic Syndromes

    S. Li, L. Liu, G. He and J. P. Wu, Food Funct., 2017, Accepted Manuscript , DOI: 10.1039/C7FO01323J

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