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Detailed phytochemical characterization and bioactive properties of Myrtus nivelii Batt & Trab.

Abstract

The endemic Algerian myrtle, Myrtus nivelii Batt & Trab., was evaluated for its bioactive properties, such as antioxidant, anti-inflammatory, cytotoxic and antibacterial activities, and correlated to the individual phenolic compounds identified in its crude aqueous extract and subsequent organic fractions (ethyl acetate and butanol). Flavonols, such as myricetin, kaempferol and quercetin glycoside derivatives were the major phenolic compounds found, being also identified the presence of ellagitannins. The ethyl acetate fraction contained the highest amount of phenolic compounds, followed by the butanol fraction and, finally, the crude aqueous extract. In general, all samples exhibited an excellent bioactivity, namely the ethyl acetate fraction that presented strong antioxidant activity, when compared to the standard trolox, strong cytotoxicity and antibacterial activity, especially against MRSA and MSSA. The present study revealed that the ethyl acetate fraction of M. nivelii could be used as source of bioactive compounds for food and pharmaceutical industries.

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Publication details

The article was received on 19 May 2017, accepted on 10 Jul 2017 and first published on 12 Jul 2017


Article type: Paper
DOI: 10.1039/C7FO00744B
Citation: Food Funct., 2017, Accepted Manuscript
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    Detailed phytochemical characterization and bioactive properties of Myrtus nivelii Batt & Trab.

    W. Rached, M. Bennaceur, L. Barros, R. C. Calhelha, S. A. Heleno, M. J. Alves, A. M. Carvalho, A. Marouf and I. C. F. R. Ferreira, Food Funct., 2017, Accepted Manuscript , DOI: 10.1039/C7FO00744B

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