Jump to main content
Jump to site search

Issue 6, 2017
Previous Article Next Article

Investigation of mechanisms involved in postprandial glycemia and insulinemia attenuation with dietary fibre consumption

Author affiliations

Abstract

This work examines the mechanisms involved in the attenuation of postprandial glycemic and insulinemic responses associated with soluble dietary fibre (SDF) consumption. The effect of SDF, including yellow mustard mucilage, soluble flaxseed gum and fenugreek gum on in vitro amylolysis and maltose transport was studied. Furthermore, a human clinical trial was conducted to investigate the effect of SDF consumption on postprandial glycemic and insulinemic responses and gastric emptying, as estimated based on the absorption of paracetamol. Participants (n = 15) at risk for type II diabetes consumed maltose syrup- and starch-based pudding treatments supplemented with each SDF, each at a concentration to match three times the apparent viscosity (18.54 mPa s at 60 s−1) equivalent to the European Food Safety Authority (2011) glycemia control health claim for cereal β-glucan, measured under simulated small intestinal conditions. The presence of each SDF delayed in vitro amylolysis to a similar extent, but had no effect on maltose transport. Generally, all SDF-containing treatments attenuated blood glucose and plasma insulin peak concentrations and plasma paracetamol 1 h incremental area under the curve values to a similar extent, relative to the controls, despite differences in the amounts at which each SDF was used (from 5.9 to 15.5 g). The postprandial attenuations were related to the ability of each SDF to modify digesta viscosity, perhaps through the delay of gastric emptying, as a delay of amylolysis and sugar transport under simulated upper intestinal conditions did not seem to have a substantial effect.

Graphical abstract: Investigation of mechanisms involved in postprandial glycemia and insulinemia attenuation with dietary fibre consumption

Back to tab navigation

Publication details

The article was received on 28 Feb 2017, accepted on 09 May 2017 and first published on 12 May 2017


Article type: Paper
DOI: 10.1039/C7FO00331E
Citation: Food Funct., 2017,8, 2142-2154
  •   Request permissions

    Investigation of mechanisms involved in postprandial glycemia and insulinemia attenuation with dietary fibre consumption

    N. Repin, B. A. Kay, S. W. Cui, A. J. Wright, A. M. Duncan and H. Douglas Goff, Food Funct., 2017, 8, 2142
    DOI: 10.1039/C7FO00331E

Search articles by author

Spotlight

Advertisements