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Non-edible parts of Solanum stramoniifolium Jacq.– a new potent source of bioactive extracts rich in phenolic compounds for functional foods

Abstract

Extracts prepared from leaves, roots, and stems of Solanum stramoniifolium Jacq. (Solanaceae) in 80% ethanol have been tested for their in vitro antioxidant, anti-inflammatory, antimicrobial, and cytotoxic activities in aim to find new sources of substances for functional foods and food additives. The root extract revealed the highest antioxidant activity in all assays exceeding the trolox capacity, and was the only extract that inhibited the nitric oxide production in mouse macrophage cells, showing also the capacity to suppress the growth of all tested human tumor cell lines (MCF-7, NCI-H460, HeLa and HepG2). The leaf extract showed the strongest antimicrobial activity inhibiting all tested clinical isolates. To the author’s best knowledge it was the first time that all individual parts of this plant were tested for biological activity together with the phenolic compounds characterization.

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Publication details

The article was received on 21 Feb 2017, accepted on 17 Apr 2017 and first published on 21 Apr 2017


Article type: Paper
DOI: 10.1039/C7FO00297A
Citation: Food Funct., 2017, Accepted Manuscript
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    Non-edible parts of Solanum stramoniifolium Jacq.– a new potent source of bioactive extracts rich in phenolic compounds for functional foods

    B. Svobodova, L. Barros, T. Sopik, R. C. Calhelha, S. A. Heleno, M. J. Alves, S. Walcott, V. Kuban and I. C. F. R. Ferreira, Food Funct., 2017, Accepted Manuscript , DOI: 10.1039/C7FO00297A

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