Prebiotics increase heme iron bioavailability and do not affect non heme iron bioavailability in humans
The aim of this study was to establish the effect of a prebiotics mix on heme and non heme iron (Fe) bioavailability in humans. To this purpose, twenty-four healthy women were randomized into one of two study groups. One group ate one yogurt per day for 12 days with a prebiotic mix (prebiotic group) and the other group received the same yogurt but without prebiotics (control group). Before and after the intake period, subjects participated in Fe absorption studies. These studies used 55Fe and 59Fe radioactive isotopes as markers of heme Fe and non heme Fe, respectively and Fe absorption was measured by the incorporation of radioactive Fe into erythrocytes. The results showed there were no significant differences in heme and non heme Fe bioavailability in the control group. Heme Fe bioavailability of prebiotic group increased significantly by 56% post-prebiotic intake. There were no significant differences in non heme Fe bioavailability in this group. We concluded that daily consumption of prebiotics mix increases heme Fe bioavailability and does not affect non heme iron bioavailability.