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The influence of chemical degradation during dietary exposures to fish on biomagnification factors and bioaccumulation factors

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Abstract

The chemical dietary absorption efficiency (ED) quantifies the amount of chemical absorbed by an organism relative to the amount of chemical an organism is exposed to following ingestion. In particular, ED can influence the extent of bioaccumulation and biomagnification for hydrophobic chemicals. A new ED model is developed to quantify chemical process rates in the gastrointestinal tract (GIT). The new model is calibrated with critically evaluated measured ED values (n = 250) for 80 hydrophobic persistent chemicals. The new ED model is subsequently used to estimate chemical reaction rate constants (kR) assumed to occur in the lumen of the GIT from experimental dietary exposure tests (n = 255) for 165 chemicals. The new kR estimates are corroborated with kR estimates for the same chemicals from the same data derived previously by other methods. The roles of kR and the biotransformation rate constant (kB) on biomagnification factors (BMFs) determined under laboratory test conditions and on BMFs and bioaccumulation factors (BAFs) in the environment are examined with the new model. In this regard, differences in lab and field BMFs are highlighted. Recommendations to address uncertainty in ED and kR data are provided.

Graphical abstract: The influence of chemical degradation during dietary exposures to fish on biomagnification factors and bioaccumulation factors

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Publication details

The article was received on 10 Nov 2017, accepted on 21 Dec 2017 and first published on 22 Dec 2017


Article type: Paper
DOI: 10.1039/C7EM00539C
Citation: Environ. Sci.: Processes Impacts, 2018, Advance Article
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    The influence of chemical degradation during dietary exposures to fish on biomagnification factors and bioaccumulation factors

    J. A. Arnot and D. Mackay, Environ. Sci.: Processes Impacts, 2018, Advance Article , DOI: 10.1039/C7EM00539C

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