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Protein Staining Agents from Low Toxic Platinum(II) Complexes with Bidentate Ligand

Abstract

Three new luminescent platinum(II) complexes with bidentate C^N and O^O ligands have been designed and synthesized in this work. Along with the changing of C^N ligands, the emission peaks of these complexes are ranging from 489-629 nm and the photoluminescent quantum efficiencies are up to 55% at room temperature. DFT and TD-DFT calculations have also been employed to investigate the ground and excited states of these platinum(II) complexes. Most importantly, these platinum(II) complexes with bidentate ligands have almost no cytotoxicity towards HeLa cells and their applications in living cell imaging and protein staining are focused in this work.

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Publication details

The article was received on 10 Aug 2017, accepted on 01 Dec 2017 and first published on 01 Dec 2017


Article type: Paper
DOI: 10.1039/C7DT02970E
Citation: Dalton Trans., 2017, Accepted Manuscript
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    Protein Staining Agents from Low Toxic Platinum(II) Complexes with Bidentate Ligand

    Y. Zhou, J. Jia, L. Cai and Y. Huang, Dalton Trans., 2017, Accepted Manuscript , DOI: 10.1039/C7DT02970E

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