Issue 35, 2017
From the journal:

Dalton Transactions

Phototoxicity of strained Ru(ii) complexes: is it the metal complex or the dissociating ligand?†

Daniel F. Azar, ORCID logo a   Hassib Audi, ORCID logo a   Stephanie Farhat,a   Mirvat El-Sibai,a   Ralph J. Abi-Habiba  and  Rony S. Khnayzer ORCID logo *a  

* Corresponding authors

a Department of Natural Sciences, Lebanese American University, Chouran, Beirut 1102-2801, Lebanon
E-mail: rony.khnayzer@lau.edu.lb

Abstract

A photochemically dissociating ligand in Ru(bpy)2(dmphen)Cl2 [bpy = 2,2′-bipyridine; dmphen = 2,9-dimethyl-1,10-phenanthroline] was found to be more cytotoxic on the ML-2 Acute Myeloid Leukemia cell line than Ru(bpy)2(H2O)22+ and prototypical cisplatin. Our findings illustrate the potential potency of diimine ligands in photoactivatable Ru(II) complexes.

Graphical abstract: Phototoxicity of strained Ru(ii) complexes: is it the metal complex or the dissociating ligand?

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Article information

DOI
https://doi.org/10.1039/C7DT02255G
Article type
Communication
Submitted
21 Jun 2017
Accepted
12 Jul 2017
First published
13 Jul 2017
This article is Open Access
Creative Commons BY-NC license

Dalton Trans., 2017,46, 11529-11532

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Phototoxicity of strained Ru(II) complexes: is it the metal complex or the dissociating ligand?

D. F. Azar, H. Audi, S. Farhat, M. El-Sibai, R. J. Abi-Habib and R. S. Khnayzer, Dalton Trans., 2017, 46, 11529 DOI: 10.1039/C7DT02255G

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