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Phototoxicity of Strained Ru(II) Complexes: Is it the Metal Complex or the Dissociating Ligand?

Abstract

A photochemically dissociating ligand in Ru(bpy)2(dmphen)Cl2 [bpy = 2,2’-bipyridine; dmphen = 2,9-dimethyl-1,10-phenanthroline] was found to be more cytotoxic on ML-2 cancer cell line than Ru(bpy)2(H2O)22+ and the prototypical cisplatin. Our findings illustrate the potential potency of diimine ligands in photoactivatable Ru(II) complexes.

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Publication details

The article was received on 21 Jun 2017, accepted on 12 Jul 2017 and first published on 13 Jul 2017


Article type: Communication
DOI: 10.1039/C7DT02255G
Citation: Dalton Trans., 2017, Accepted Manuscript
  • Open access: Creative Commons BY-NC license
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    Phototoxicity of Strained Ru(II) Complexes: Is it the Metal Complex or the Dissociating Ligand?

    D. Azar, H. Audi, S. Farhat, M. El Sibai, R. Abi-Habib and R. S. Khnayzer, Dalton Trans., 2017, Accepted Manuscript , DOI: 10.1039/C7DT02255G

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