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A Perspective – can copper complexes be developed as a novel class of therapeutics?

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Abstract

Although copper–ligand complexes appear to be promising as a new class of therapeutics, other than the family of copper(II) coordination compounds referred to as casiopeínas these compounds have yet to reach the clinic for human use. The pharmaceutical challenges associated with developing copper-based therapeutics will be presented in this article along with a discussion of the potential for high-throughput chemistry, computer-aided drug design, and nanotechnology to address the development of this important class of drug candidates.

Graphical abstract: A Perspective – can copper complexes be developed as a novel class of therapeutics?

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Publication details

The article was received on 29 May 2017, accepted on 04 Jul 2017 and first published on 04 Jul 2017


Article type: Perspective
DOI: 10.1039/C7DT01955F
Citation: Dalton Trans., 2017, Advance Article
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    A Perspective – can copper complexes be developed as a novel class of therapeutics?

    M. Wehbe, A. W. Y. Leung, M. J. Abrams, C. Orvig and M. B. Bally, Dalton Trans., 2017, Advance Article , DOI: 10.1039/C7DT01955F

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