Jump to main content
Jump to site search

Issue 42, 2017
Previous Article Next Article

Fast and cost-effective cyclotron production of 61Cu using a natZn liquid target: an opportunity for radiopharmaceutical production and R&D

Author affiliations

Abstract

Following our previous work on the production of radiometals, such as 64Cu and 68Ga, through the irradiation of liquid targets using a medical cyclotron, we describe in this paper a technique to produce 61Cu through the irradiation of natural zinc using a liquid target. The proposed method is very cost-effective, as it avoids the use of expensive enriched material, and is fast, as a purified solution of 61CuCl2 is obtained in less than 30 min after the end of beam. Considering its moderate half-life of 3.33 h and favourable decay properties as a positron emitter, 61Cu is a very attractive nuclide for the labelling of PET tracers for pre-clinical and clinical use with PET as well as to support the intense R&D programmes being carried out worldwide by taking advantage of the rich and versatile chemistry of copper.

Graphical abstract: Fast and cost-effective cyclotron production of 61Cu using a natZn liquid target: an opportunity for radiopharmaceutical production and R&D

Back to tab navigation

Publication details

The article was received on 19 May 2017, accepted on 27 Jun 2017 and first published on 27 Jun 2017


Article type: Paper
DOI: 10.1039/C7DT01836C
Citation: Dalton Trans., 2017,46, 14556-14560
  •   Request permissions

    Fast and cost-effective cyclotron production of 61Cu using a natZn liquid target: an opportunity for radiopharmaceutical production and R&D

    S. J. C. do Carmo, V. H. P. Alves, F. Alves and A. J. Abrunhosa, Dalton Trans., 2017, 46, 14556
    DOI: 10.1039/C7DT01836C

Search articles by author

Spotlight

Advertisements