Jump to main content
Jump to site search


Controllable n-Fe2O3@graphene nanomaterials by ALD applied in an aptasensor with enhanced electrochemical performance for thrombin detection

Author affiliations

Abstract

An elegant atomic layer deposition (ALD) method has been employed for the controllable preparation of a uniform Fe2O3-coated graphene nanostructure (Fe2O3@graphene). The Fe2O3 coating thickness of the Fe2O3@graphene nanostructure can be tuned by varying the cycle number of Fe2O3 ALD. The produced Fe2O3@graphene composites are characterized by transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), Raman spectroscopy and cyclic voltammetry (CV). It is revealed that Fe2O3 is effectively deposited on the surface of graphene. Combined with the high affinity and specificity of an aptamer, a simple, rapid and sensitive electrochemical aptasensor was successfully fabricated for thrombin detection. The resulting electrochemical aptasensor displays a linear response to thrombin in the 1.0 × 10−11 to 4.0 × 10−9 M concentration range with the detection limit of 1.0 × 10−12 M (at an S/N of 3). The described controllable multifunctional graphene nanomaterials from ALD are expected to be applied in a biosensing platform which will exhibit wide applications in biological, medical, and environmental fields.

Graphical abstract: Controllable n-Fe2O3@graphene nanomaterials by ALD applied in an aptasensor with enhanced electrochemical performance for thrombin detection

Back to tab navigation
Please wait while Download options loads

Publication details

The article was received on 08 Apr 2017, accepted on 05 May 2017 and first published on 05 May 2017


Article type: Paper
DOI: 10.1039/C7DT01184A
Citation: Dalton Trans., 2017, Advance Article
  •   Request permissions

    Controllable n-Fe2O3@graphene nanomaterials by ALD applied in an aptasensor with enhanced electrochemical performance for thrombin detection

    H. Zhang, B. Zhang, A. Chen and Y. Qin, Dalton Trans., 2017, Advance Article , DOI: 10.1039/C7DT01184A

Search articles by author