Jump to main content
Jump to site search

Issue 10, 2017
Previous Article Next Article

Benzodiazines: recent synthetic advances

Author affiliations


Benzodiazines (diazonaphthalenes with both nitrogens in the same ring) – cinnolines (1,2-benzodiazine), quinazolines (1,3-benzodiazine), phthalazines (2,3-benzodiazine) and quinoxalines (1,4-benzodiazine) – are important class of compounds with broad biological properties and wide application in pharmaceutical as well as agrochemical arenas. These diazaheterocycles are present in a wide variety of bioactive natural products as well as synthetic molecules that are good drug candidates constituting key structural units responsible for their pronounced therapeutic activities. Their rapidly growing uses and applications in medicinal and agrochemical arenas prompt the researchers for further studies on this important group of compounds. In this review, we hope to provide a brief overview of the important general methodologies and recent developments towards their synthesis and open the door for further progress in this area.

Graphical abstract: Benzodiazines: recent synthetic advances

Back to tab navigation

Publication details

The article was received on 31 Jan 2017 and first published on 28 Apr 2017

Article type: Review Article
DOI: 10.1039/C7CS00082K
Citation: Chem. Soc. Rev., 2017,46, 3060-3094
  •   Request permissions

    Benzodiazines: recent synthetic advances

    T. Mathew, A. Á. Papp, F. Paknia, S. Fustero and G. K. Surya Prakash, Chem. Soc. Rev., 2017, 46, 3060
    DOI: 10.1039/C7CS00082K

Search articles by author