Jump to main content
Jump to site search


Radical cascade cyclization of 1,n-enynes and diynes for the synthesis of carbocycles and heterocycles

Author affiliations

Abstract

Carbo- and heterocycles are widely found in natural products, biologically active structures, medicinally relevant compounds, and in many other fine chemicals. The development of novel, general and efficient methods for their construction has therefore gained great interest in synthetic organic chemistry. Recently, radical chemistry has become a heavily investigated research field (a renaissance!). Along these lines, radical cascade cyclization of 1,n-enynes and diynes has emerged as a powerful strategy for the preparation of carbo- and heterocycles. In this review, we highlight recent advances in this rapidly growing area also focusing on reaction mechanisms.

Graphical abstract: Radical cascade cyclization of 1,n-enynes and diynes for the synthesis of carbocycles and heterocycles

Back to tab navigation

Publication details

The article was received on 14 Dec 2016 and first published on 06 Jun 2017


Article type: Review Article
DOI: 10.1039/C6CS00912C
Citation: Chem. Soc. Rev., 2017, Advance Article
  •   Request permissions

    Radical cascade cyclization of 1,n-enynes and diynes for the synthesis of carbocycles and heterocycles

    J. Xuan and A. Studer, Chem. Soc. Rev., 2017, Advance Article , DOI: 10.1039/C6CS00912C

Search articles by author

Spotlight

Advertisements