Jump to main content
Jump to site search

Issue 24, 2017
Previous Article Next Article

On the mechanism of mechanochemical molecular encapsulation in peptidic capsules

Author affiliations

Abstract

Molecular encapsulation of C60 inside a hydrogen-bond-sealed semi-flexible peptidic capsule is hindered in solution, yet it proceeds effectively after mechanical milling of a solid sample. We show that the molecular mechanism involves the generation of non-covalently disordered forms that are active in guest uptake. We also show that the solvent-free mechanochemical covalent synthesis of capsules directly results in obtaining disordered, active forms.

Graphical abstract: On the mechanism of mechanochemical molecular encapsulation in peptidic capsules

Back to tab navigation

Supplementary files

Publication details

The article was received on 20 Apr 2017, accepted on 26 May 2017 and first published on 09 Jun 2017


Article type: Communication
DOI: 10.1039/C7CP02603J
Citation: Phys. Chem. Chem. Phys., 2017,19, 15676-15680
  •   Request permissions

    On the mechanism of mechanochemical molecular encapsulation in peptidic capsules

    M. P. Szymański, H. Jędrzejewska, M. Wierzbicki and A. Szumna, Phys. Chem. Chem. Phys., 2017, 19, 15676
    DOI: 10.1039/C7CP02603J

Search articles by author

Spotlight

Advertisements